Below is a summary for the TRIO gene observed in research publications. This is not meant to take the place of medical advice. Click HERE for the full gene guide, which includes more information, such as chance of having another child with this condition, or specialists to consider for people with this condition.
What is TRIO-related syndrome?
TRIO-related syndrome happens when there are changes to the TRIO gene. These changes can keep the gene from working as it should.
The TRIO gene plays a key role in the basic function of the cell.
Because the TRIO gene is important in the development and function of brain cells, many people who have TRIO-related syndrome have:
- Intellectual disability
- Motor and language delays
- Behavior issues, such as autism
Do people who have TRIO-related syndrome look different?
People who have TRIO-related syndrome may look different. One study of 10 people found that one-half had a small lower jaw and facial asymmetry, meaning the left half of the face looked different from the right half. Some have short tapered fingers.
How many people have ADNP-related syndrome?
As of 2020, about 20 people in the world with changes in the TRIO gene had been described in the medical literature.
Research Article Summary