CHD8

Learn more about the CHD8 gene and connect with other Simons Searchlight families with the resources below:

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Support Resources

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Research Article Summaries

Below, we have summarized research articles about changes in the CHD8 gene. We hope you find this information helpful.

The information available about CHD8 is limited, and families and doctors share a critical need for more information. As we learn more from children who have a change in this gene, we expect this list of resources and information to grow.

You can also visit the Simons Foundation’s SFARI Gene website to see information for researchers about this gene.

 

CHD8 intragenic deletion associated with autism spectrum disorder

Original research article by E.S. Stolerman et al. (2016).

Read the abstract here and the Simons Searchlight summary here.

 

Disruptive CHD8 mutations define a subtype of autism early in development

Original research article by R. Bernier et al. (2014).

Read the article here and the Simons Searchlight summary here.

 

Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations

Original research article by B. O’Roak et al. (2012).

Read the article here and the Simons Searchlight summary here.

 

Multiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disorders

Original research article by B. O’Roak et al. (2012).

Read the abstract here and the Simons Searchlight summary here.

 

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Research Opportunities

Simons Searchlight

Help the Simons Searchlight team learn more about CHD8 genetic changes by taking part in our research. You can learn more about the project and sign up here.

TIGER Study

The University of Washington’s Autism Center seeks to better understand the medical, learning, and behavioral features of people with changes in CHD8.

Click here to learn more about this opportunity.

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Family Stories

Stories from CHD8 families:

Click here to share your family’s story!