Below is a summary for the NR4A2 gene observed in research publications. This is not meant to take the place of medical advice.
The online Gene Guide includes more information about NR4A2 -related syndrome such as the chance of having another child with this condition, behavior and development concerns linked to NR4A2 -related syndrome or specialists to consider for people with this condition. Share this resource with family members or your clinical providers.
What is NR4A2 -related syndrome?
NR4A2 -related syndrome happens when there are changes to the NR4A2 gene. These changes can keep the gene from working as it should.
NR4A2 plays a key role in the development of the brain. This gene is particularly important in brain cells that help control movement, emotion, and memory.
NR4A2 -related syndrome can have moderate to severe effects on the development of communication skills, social skills, and learning skills. Because the NR4A2 gene is important in the development of the brain, many people who have NR4A2 -related syndrome have:
- Language impairment
- Intellectual disability
Research Article Summaries