Below is a summary for the MAOA gene observed in research publications. This is not meant to take the place of medical advice.
What is Brunner syndrome?
Brunner syndrome happens when there are changes in the MAOA gene. These changes can keep the gene from working as it should.
The MAOA protein is important for mitochondria, which are the powerhouse of the cell.
Because the MAOA gene is important for the brain, some people may have:
- Intellectual disability
- Learning issues
- Disturbed sleep and night terrors
- Episodic headaches
- Attention deficit hyperactivity disorder, or ADHD
- Antisocial behavior
- Behavior issues and temper tantrums
Brunner syndrome mostly affects males, but some females might have symptoms.
Do people who have Brunner syndrome look different?
Most people who have Brunner syndrome do not look different. Some people might flush, or often look like they are blushing.
How many people have Brunner syndrome?
As of 2022, at least 10 people in the world with Brunner syndrome have been described in medical research.
Research Article Summaries