Below is a summary for the GRIN1 gene observed in research publications. This is not meant to take the place of medical advice.
The online Gene Guide includes more information about GRIN1 such as the chance of having another child with this condition, behavior and development concerns linked to GRIN1-related syndrome or specialists to consider for people with this condition. Share this resource with family members or your clinical providers.
What is GRIN1-related syndrome?
GRIN1-related syndrome happens when there are changes to the GRIN1 gene. These changes can keep the gene from working as it should.
The GRIN1 gene plays a key role in communication between brain cells, memory, and learning.
Because the GRIN1 gene is important in the development and function of brain cells, many people who have GRIN1-related syndrome have:
- Intellectual disability
- Developmental delay
- Low muscle tone
- Movement disorders
How many people have GRIN1-related syndrome?
As of 2021, about 72 people in the world with changes in the GRIN1 gene had been described in medical research.
Research Article Summaries