Below is a summary for the FOXP1 gene observed in research publications. This is not meant to take the place of medical advice.
The online Gene Guide includes more information about FOXP1 such as the chance of having another child with this condition, behavior and development concerns linked to FOXP1-related syndrome or specialists to consider for people with this condition. Share this resource with family members or your clinical providers.
What is FOXP1-Related Syndrome?
FOXP1-related syndrome happens when there are changes to the FOXP1 gene. These changes can keep the gene from working as it should.
The FOXP1 gene is important in the development of the brain and body. It plays a key role in areas of the brain that control language.
The FOXP1 gene can also affect the development of other body parts, including the heart, ears, eyes, and genitals. FOXP1-related syndrome can have mild to moderate effects on the development of communication and social and learning skills. It can affect how a person acts or interacts with others.
Because the FOXP1 gene is important in the development and function of brain cells, many people who have FOXP1-related syndrome have:
- Delayed development and/or intellectual disability.
- Speech and language delay.
- Autism spectrum disorder or features of autism.
- Other behavioral issues.
How many people have FOXP1-related syndrome?
As of 2018, doctors had found about 50 people in the world with changes in the FOXP1 gene. The first case of FOXP1-related syndrome was described in 2009. Scientists expect to find more people who have the syndrome as access to genetic testing improves.
Research Article Summaries