De novo mutations in FOXP1 in cases with intellectual disability, autism and language impairment
Original research article by F.F. Hamdan et al. (2010)
Read the abstract here.
The FOXP1 gene is believed to play an important role in language development. This study compared typically developing children with children who have intellectual disability and/or autism to look for differences in the FOXP1 gene. Of the 245 people studied with intellectual disability or autism, two had a change in this gene that their parents did not have. Both people had some degree of intellectual disability, language impairment, autism/autistic features, and behavior problems.