Below is a summary for the ANK3 gene observed in research publications. This is not meant to take the place of medical advice.
What is ANK3-related disorder?
Because ANK3 is so new in autism, we don’t have specific information on what medical problems you might expect now and in the near future. We can tell you that ANK3 plays an important role in brain development and is associated with autism. The gene is also likely associated with language and learning.
Why does my child have a change in the ANK3 gene?
No parent causes their child’s de novo gene change. We know this because no parent has any control over the gene changes that they do or do not pass on to their children. Please keep in mind that nothing a parent does before or during the pregnancy causes this to happen. The gene change takes place on its own and cannot be predicted or stopped.
How many people have a de novo gene change in the ANK3 gene?
As of 2019, researchers had found fewer than 10 people in the world with autism or neurodevelopmental disorders and changes in the ANK3 gene. Scientists expect to find more people who have the condition as access to genetic testing improves.
How are people who have changes in ANK3 treated?
Scientists and doctors have only just begun to study people who have changes in the ANK3 gene. At this point, there are no medicines designed to treat the condition. A genetic diagnosis can help people decide on the best way to track the condition and manage therapies. Doctors can refer people to specialists for:
- Physical exams and brain studies.
- Genetics consults.
- Developmental and behavior studies.
- Other issues, as needed.
Research Article Summaries