Below is a summary for the ANK3 gene observed in research publications. This is not meant to take the place of medical advice.

Click here for our full ANK3 Gene Guide

The online Gene Guide includes more information about ANK3 such as the chance of having another child with this condition, behavior and development concerns linked to ANK3-related syndrome or specialists to consider for people with this condition. Share this resource with family members or your clinical providers.

What is ANK3-related disorder?

Because ANK3 is so new in autism, we don’t have specific information on what medical problems you might expect now and in the near future. We can tell you that ANK3 plays an important role in brain development and is associated with autism. The gene is also likely associated with language and learning.

How many people have a de novo gene change in the ANK3 gene?

As of 2019, researchers had found fewer than 10 people in the world with autism or neurodevelopmental disorders and changes in the ANK3 gene. Scientists expect to find more people who have the condition as access to genetic testing improves.


Support Resources

  • Simons Searchlight Community – ANK3 Facebook group
  • Geisinger Developmental Brain Disorder Gene Database – ANK3


GeneReviews are a great resource to bring to your child’s clinicians. These publications provide a summary of current research on genetic conditions and information on ongoing care.

There is currently no GeneReviews for ANK3.


Research Article Summaries

We currently do not have any article summaries for ANK3, but we add resources to our website as they become available.

The information available about ANK3 is limited, and families and doctors share a critical need for more information. As we learn more from children who have this gene change, we expect our list of resources and information to grow.

Full versions of published research articles can be found on PubMed. PubMed is a National Institutes of Health (NIH) online database that is free. It has a collection of both medical and scientific research articles. A PubMed search for ANK3 articles can be found here.

You can also visit the Simons Foundation’s SFARI Gene website to see information for researchers about this gene.


Research Opportunities

Simons Searchlight

Help the Simons Searchlight team learn more about ANK3 genetic changes by taking part in our research. You can learn more about the project and sign up here.


Family Stories

We do not currently have any stories from ANK3 families.

Click here to share your family’s story!