16p13.11 Deletion

Below is a summary for the 16p13.11 Deletion observed in research publications. This is not meant to take the place of medical advice.

What is 16p13.11 deletion syndrome?

16p13.11 deletion syndrome can have moderate to severe effects on communication, social, and learning skills.


People who have 16p13.11 deletion syndrome may have:

  • Intellectual disability
  • Autism
  • Small head size
  • Seizures

Do people who have 16p13.11 deletion syndrome look different?

People who have 16p13.11 deletion syndrome do not look very different.

Behavior and development concerns linked to 16p13.11 deletion syndrome:

  • Learning: Learning problems are common in people who have 16p13.11 deletion syndrome. Combined results from different studies suggest that about 70 percent, or 23/32 people, have intellectual disability.
  • Speech: Language delay and speech impairment are common.
  • Behavior: Some people who have 16p13.11 deletion syndrome have autism, obsessive compulsive disorder, or Tourette’s syndrome, a disorder with involuntary tics and repeated sounds.

Support Resources



GeneReviews are a great resource to bring to your child’s clinicians. These publications provide a summary of current research on genetic conditions and information on ongoing care.

There is currently no GeneReviews for 16p13.11 Deletions.


Research Article Summaries

We currently do not have any article summaries for 16p13.11 Deletion, but we add resources to our website as they become available.

The information available about 16p13.11 Deletion is limited, and families and doctors share a critical need for more information. As we learn more from children who have this gene change, we expect our list of resources and information to grow.


Research Opportunities

Simons Searchlight

Help the Simons Searchlight team learn more about 16p13.11 deletions by taking part in our research. You can learn more about the project and sign up here.


Family Stories

We do not currently have any stories from 16p13.11 Deletion families.

Click here to share your family’s story!