Below is a summary for the TANC2 gene observed in research publications. This is not meant to take the place of medical advice.
The online Gene Guide includes more information about TANC2 such as the chance of having another child with this condition, behavior and development concerns linked to TANC2-related syndrome or specialists to consider for people with this condition. Share this resource with family members or your clinical providers.
What is TANC2-related Syndrome?
TANC2-related syndrome happens when there are changes to the TANC2 gene. These changes can keep the gene from working as it should.
The TANC2 gene helps to control the connections between brain cells.
Because the TANC2 gene is important in the development and function of brain cells, many people who have TANC2-related syndrome have:
- Intellectual disability
- Delayed language
- Delayed motor development
How many people have TANC2-related syndrome?
As of 2019, about 20 people in the world with changes in the TANC2 gene had been described in medical research. The first case of TANC2-related syndrome was described in 2019. Scientists expect to find more people who have the syndrome as access to genetic testing improves.
Research Article Summaries