Below is a summary for the GIGYF1 gene observed in research publications. This is not meant to take the place of medical advice.

Click here for our full GIGYF1 Gene Guide

The online Gene Guide includes more information about GIGYF1 such as the chance of having another child with this condition, behavior and development concerns linked to GIGYF1-related syndrome or specialists to consider for people with this condition. Share this resource with family members or your clinical providers.

What is GIGYF1-related syndrome?

GIGYF1 is so new in autism, we don’t have specific information on what medical issues you might expect now and in the near future.

Key Role

We can tell you that GIGYF1 plays an important role in brain development and is associated with autism. The gene is also likely associated with language and learning.


Symptoms of GIGYF1-related syndrome are not yet known.

How many people have GIGYF1-related syndrome?

As of 2019, fewer than 12 people in the world with changes in GIGYF1 gene and autism or neurodevelopmental disorders have been described in medical research. The first case of this condition was described in 2014. Scientists expect to find more people who have the condition as access to genetic testing improves.


Support Resources


Research Article Summaries

We currently do not have any article summaries for GIGYF1, but we add resources to our website as they become available.

The information available about GIGYF1 is limited, and families and doctors share a critical need for more information. As we learn more from children who have this gene change, we expect our list of resources and information to grow.

Full versions of published research articles can be found on PubMed. PubMed is a National Institutes of Health (NIH) online database that is free. It has a collection of both medical and scientific research articles. A PubMed search for GIGYF1 articles can be found here.

You can also visit the Simons Foundation’s SFARI Gene website to see information for researchers about this gene.


Research Opportunities

Simons Searchlight

Help the Simons Searchlight team learn more about GIGYF1 genetic changes by taking part in our research. You can learn more about the project and sign up here.


Family Stories

We do not currently have any stories from GIGYF1 families.

Click here to share your family’s story!