Below is a summary for the NLGN2 gene observed in research publications. This is not meant to take the place of medical advice.
What is NLGN2-related syndrome?
NLGN2-related syndrome most often happens when there are changes in the NLGN2 gene. These changes can keep the gene from working as it should.
The NLGN2 gene plays an important role in the development of connections in the brain.
Because the NLGN2 gene is important for the brain, some people may have:
- Intellectual disability
- Obsessive compulsive disorder
- Developmental delay
Do people who have NLGN2-related syndrome look different?
People who have NLGN2-related syndrome may look different. Appearance can vary and can include some but not all of these features:
- Larger than average head size
- Changes in facial features, which might not be the same in every person
How many people have NLGN2-related syndrome?
NLGN2-related syndrome is very rare. As of 2022, about 8 people in the world with NLGN2-related syndrome have been described in medical research.
Research Article Summaries