HNRNPD
The information for this summary of HNRNPD-related syndrome comes from research publications. This is not meant to take the place of medical advice.
Click here for our full HNRNPD Gene Guide
The online Gene Guide includes more information about HNRNPD such as the chance of having another child with this condition, behavior and development concerns linked to HNRNPD-related syndrome or specialists to consider for people with this condition. Share this resource with family members or your clinical providers.
What is HNRNPD-related syndrome?
HNRNPD-related syndrome happens when there are changes in the HNRNPD gene. These changes can keep the gene from working as it should.
Key Role
The HNRNPD protein binds to a molecule in the cell called RNA. RNA is made from a DNA sequence and is needed for the cell to make proteins. The HNRNPD gene may play an important role in the development of the brain.
Symptoms
Because the HNRNPD gene might be important in development, some people may have:
- Developmental delay
- Intellectual disability
- Speech delay
- Emotional or behavioral issues
- Attention-deficit/hyperactivity disorder (ADHD)
- Seizures
How many people have HNRNPD-related syndrome?
As of 2025, about 13 people in the world with an HNRNPD genetic variant have been identified in medical research.
Support Resources
- HNRNP-Related Parent Connect – Facebook group
Research Opportunities
Simons Searchlight
Help the Simons Searchlight team learn more about HNRNPD genetic changes by taking part in our research. You can learn more about the project and sign up here.
Family Stories
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