Below is a summary for the DYRK1A gene observed in research publications. This is not meant to take the place of medical advice.
The online Gene Guide includes more information about DYRK1A such as the chance of having another child with this condition, behavior and development concerns linked to DYRK1A -related syndrome or specialists to consider for people with this condition. Share this resource with family members or your clinical providers.
The latest Simons Searchlight report includes updated information on your genetic community and features a special spotlight on behavioral and emotional concerns in children using results from the Child Behavior Checklist (CBCL).
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View all reports below by clicking on “Previous Registry Reports” at the bottom of this page.
What is DYRK1A -Related Syndrome?
DYRK1A -related syndrome happens when there are changes to the DYRK1A gene. These changes can keep the gene from working as it should.
The DYRK1A gene plays a key role in brain development. It is especially important for creating new brain cells and for updating connections among brain cells.
Because the DYRK1A gene is important in brain development, many people who have DYRK1A -related syndrome have:
- Intellectual disability
- Speech delay
- Motor difficulties
- Small head, also called microcephaly
- Feeding problems
- Vision problems
- Behavioral issues
Research Article Summaries
Previous Registry Reports
Sources and References