CSNK2A1

Below is a summary for the CSNK2A1 gene observed in research publications. is is not meant to take the place of medical advice.

Access the Full CSNK2A1 Gene Guide

The online Gene Guide includes more information about CSNK2A1 such as the chance of having another child with this condition, behavior and development concerns linked to CSNK2A1 -related syndrome or specialists to consider for people with this condition. Share this resource with family members or your clinical providers.

Latest CSNK2A1 Report Download Report

The latest Simons Searchlight report includes updated information on your genetic community and analyzes developmental growth charts based on the Vineland Adaptive Behavior Scales (Vineland-3) survey. This data shows skills at different ages and helps doctors and researchers understand how these skills change over time. Watch our short video to understand the charts better.

Please take our surveys to contribute to this research. If you are not yet registered, consider joining Simons Searchlight to be included in future reports!

View all reports below by clicking on “Previous Registry Reports” at the bottom of this page.

What is CSNK2A1 -related syndrome?

CSNK2A1 -related syndrome happens when there are changes to the CSNK2A1 gene. These changes can keep the gene from working as it should. CSNK2A1 -related syndrome is also called Okur-Chung neurodevelopmental syndrome (OCNDS).

Key Role

The CSNK2A1 gene plays different roles in the body, including helping to control the birth of new cells and helping to control the day to night cycle of cells.

Symptoms

Because the CSNK2A1 gene is important in the development and function of brain cells, many people who have CSNK2A1 -related syndrome have:

Physical changes
Intellectual disability
Other developmental issues

Support Resources

Simons Searchlight Community: CSNK2A1 Facebook group
CSNK2A1 Foundation Website: csnk2a1foundation.org
CSNK2A1 Foundation Facebook Page: facebook.com/csnk2a1/

GeneReviews

GeneReviews are a great resource to bring to your child’s clinicians. These publications provide a summary of current research on genetic conditions and information on ongoing care.

Check out the GeneReviews for Okur-Chung Neurodevelopmental Syndrome.

Presentations

Simons Searchlight Family Research Conference 2022 Registry Update

Registry Update Slide Deck

Simons Searchlight Family & Research Conference 2021 CSNK2A1 Virtual Conference

Simons Searchlight Family & Research Conference 2020 CSNK2A1 Virtual Conference

Research Article Summaries

We currently do not have any article summaries for CSNK2A1 , but we add resources to our website as they become available. The information available about CSNK2A1 is limited, and families and doctors share a critical need for more information. As we learn more from children who have this gene change, we expect our list of resources and information to grow. Full versions of published research articles can be found on PubMed. PubMed is a National Institutes of Health (NIH) online database that is free. It has a collection of both medical and scientific research articles. A PubMed search for CSNK2A1 articles can be found here.

Research Opportunities

Simons Searchlight

Help the Simons Searchlight team learn more about CSNK2A1 genetic changes by taking part in our research. You can learn more about the project and sign up here.

External Research Opportunity: FaceMatch

FaceMatch is a platform that helps parents and doctors contribute to an international secure image database of both undiagnosed and diagnosed children across the globe. *This study is not affiliated with Simons Searchlight. Learn more about FaceMatch.

Family Stories

Stories from CSNK2A1 families:

Click here to share your family’s story!

Previous Registry Reports