Below is a summary for the MEIS2 gene observed in research publications. This is not meant to take the place of medical advice.
What is MEIS2 -related syndrome?
MEIS2 -related syndrome happens when there are changes to the MEIS2 gene. These changes can keep the gene from working as it should.
The MEIS2 gene plays a key role in the development of the brain and the heart.
Because the MEIS2 gene is important for how the brain and the heart develop, many people who have MEIS2 -related syndrome have:
- Cleft palate, an opening or split in the upper lip or roof of the mouth that occurs before birth
- Developmental delay
- Behavior concerns
- Changes in the heart
Do people who have MEIS2 -related syndrome look different?
People who have MEIS2 -related syndrome may look different. Appearance can vary and can include these features:
- Arched eyebrows
- Broad forehead with a noticeable ridge
Research Article Summaries