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Below is a summary for the MAOB gene observed in research publications. This is not meant to take the place of medical advice.
What is MAOB-associated autism?
MAOB-associated autism happens when there are changes in the MAOB gene. These changes can keep the gene from working as it should.
Key Role
The MAOB protein is important for mitochondria, which are the powerhouse of the cell.
Symptoms
Because the MAOB gene is important for the brain, some people may have:
- Parkinson-like tremors that might worsen with smoking cigarettes
- Autism
Do people who have MAOB-associated autism look different?
People who have MAOB-associated autism do not look different.
How many people have MAOB-associated autism?
MAOB-associated autism is very rare, and the number of people who have it is unknown.
Support Resources
- Simons Searchlight Community – MAOA/B Facebook group
GeneReviews
GeneReviews are a great resource to bring to your child’s clinicians. These publications provide a summary of current research on genetic conditions and information on ongoing care.
There is currently no GeneReviews for MAOB.
Research Article Summaries
We currently do not have any article summaries for MAOB, but we add resources to our website as they become available.
The information available about MAOB is limited, and families and doctors share a critical need for more information. As we learn more from children who have this gene change, we expect our list of resources and information to grow.
Full versions of published research articles can be found on PubMed. PubMed is a National Institutes of Health (NIH) online database that is free. It has a collection of both medical and scientific research articles. A PubMed search for MAOB articles can be found here.
Research Opportunities
Simons Searchlight
Help the Simons Searchlight team learn more about MAOB genetic changes by taking part in our research. You can learn more about the project and sign up here.
Family Stories
We do not currently have any stories from MAOB families.
Click here to share your family’s story!