Below is a summary for the AFF2 gene observed in research publications. This is not meant to take the place of medical advice.
The online Gene Guide includes more information about AFF2 such as the chance of having another child with this condition, behavior and development concerns linked to AFF2 -related syndrome or specialists to consider for people with this condition. Share this resource with family members or your clinical providers.
What is AFF2 -related syndrome?
AFF2 -related syndrome happens when there are changes to the AFF2 gene. These changes can keep the gene from working as it should. The AFF2 gene is also called FMR2 or FRAXE.
The AFF2 gene plays a key role in brain development.
Because the AFF2 gene is important in the development and function of brain cells, many people who have AFF2 -related syndrome have:
- Intellectual disability
- Developmental and speech delays
- Autism or features of autism
- Hyperactivity and attention difficulties
- Behavior issues
Research Article Summaries
Sources and references