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HNRNPUL2

The information for this summary of HNRNPUL2-related syndrome comes from research publications. This is not meant to take the place of medical advice.

Click here for our full HNRNPUL2 Gene Guide

The online Gene Guide includes more information about HNRNPUL2 such as the chance of having another child with this condition, behavior and development concerns linked to HNRNPUL2-related syndrome or specialists to consider for people with this condition. Share this resource with family members or your clinical providers.

What is HNRNPUL2-related syndrome?

HNRNPUL2-related syndrome happens when there are changes in the HNRNPUL2 gene. These changes can keep the gene from working as it should.

Key Role

The HNRNPUL2 gene may play an important role in human development.

Symptoms

Because the HNRNPUL2 gene is important for brain activity, many people who have HNRNPUL2-related syndrome have:

  • Development delay
  • Intellectual disability
  • Delays or difficulty in speaking
  • Seizures
  • Attention-deficit/hyperactivity disorder (ADHD)
  • Autism spectrum disorder

How many people have HNRNPUL2-related syndrome?

As of 2025, more than 20 people with HNRNPUL2-related syndrome have been identified in medical research.

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Support Resources

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Research Opportunities

Simons Searchlight

Help the Simons Searchlight team learn more about HNRNPUL2 genetic changes by taking part in our research. You can learn more about the project and sign up here.

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Family Stories

We do not currently have any stories from HNRNPUL2 families.

Click here to share your family’s story!