Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations< /strong> < /h2>

Original research article by B.J. Oâ € ™Roak et al. < /em> (2012) . < /p>

Read the abstract here< /a> . < /p>

Whole-exome sequencing was performed for 209 families (677 people) who had participated in the Simons Foundation< /span> â € ™s Simons Simplex Collection. The study included children with autism and intellectual disability. This study identified over 100 new candidate genes related to developmental delay, intellectual disability, and/or features of autism, including the  MBD5  gene (a gene known to be involved in causing intellectual disability) that was not inherited from either parent. < /p>