DST

Learn more about the DST gene and connect with other Simons Searchlight families with the resources below:

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Support Resources

  • Simons Searchlight Community – DST Facebook group
  • Geisinger Developmental Brain Disorder Gene Database – DST
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GeneReviews

Gene Reviews are a great resource to bring to your child’s clinicians. These publications provide a summary of current research on genetic conditions and information on ongoing care.

Individuals with biallelic gene changes in DST may have Epidermolysis Bullosa Simplex, briefly mentioned in the GeneReviews below.

Check out the GeneReviews for Epidermolysis Bullosa Simplex.

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Research Article Summaries

Below, we have summarized research articles about changes in the DST gene. We hope you find this information helpful.

The information available about DST is limited, and families and doctors share a critical need for more information. As we learn more from children who have a change in this gene, we expect this list of resources and information to grow.

You can also visit the Simons Foundation’s SFARI Gene website to see information for researchers about this gene.

 

Excess of rare novel loss-of-function variants in synaptic genes in schizophrenia and autism spectrum disorders

Original research article by E.M. Kenny et al. (2014).

Read the article here and the Simons Searchlight summary here.

 

De novo gene disruptions in children on the autistic spectrum

Original research article by E.M. Iossifov et al. (2012).

Read the abstract here and the Simons Searchlight summary here.

 

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Research Opportunities

Simons Searchlight

Help the Simons Searchlight team learn more about DST genetic changes by taking part in our research. You can learn more about the project and sign up here.

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Family Stories

We do not currently have any stories from DST families.

Click here to share your family’s story!